Evaluation of specific humoral immune responses in human filariasis.
Identifieur interne : 006468 ( PubMed/Curation ); précédent : 006467; suivant : 006469Evaluation of specific humoral immune responses in human filariasis.
Auteurs : H. Kumar ; A. Malhotra ; S. Santhanam ; D C Jain ; T K GhoshSource :
- Folia parasitologica [ 0015-5683 ] ; 1987.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antihelminthe (analyse), Anticorps antihelminthe (biosynthèse), Antigènes d'helminthe (immunologie), Brugia (immunologie), Contre-immunoélectrophorèse, Dirofilaria immitis (immunologie), Filarioidea (immunologie), Filariose lymphatique (immunologie), Filarioses (immunologie), Humains, Immunoglobuline G (analyse), Immunoglobuline M (analyse), Test ELISA, Wuchereria (immunologie), Wuchereria bancrofti (immunologie).
- MESH :
- analyse : Anticorps antihelminthe, Immunoglobuline G, Immunoglobuline M.
- biosynthèse : Anticorps antihelminthe.
- immunologie : Antigènes d'helminthe, Brugia, Dirofilaria immitis, Filarioidea, Filariose lymphatique, Filarioses, Wuchereria, Wuchereria bancrofti.
- Animaux, Contre-immunoélectrophorèse, Humains, Test ELISA.
English descriptors
- KwdEn :
- Animals, Antibodies, Helminth (analysis), Antibodies, Helminth (biosynthesis), Antigens, Helminth (immunology), Brugia (immunology), Counterimmunoelectrophoresis, Dirofilaria immitis (immunology), Elephantiasis, Filarial (immunology), Enzyme-Linked Immunosorbent Assay, Filariasis (immunology), Filarioidea (immunology), Humans, Immunoglobulin G (analysis), Immunoglobulin M (analysis), Wuchereria (immunology), Wuchereria bancrofti (immunology).
- MESH :
- chemical , analysis : Antibodies, Helminth, Immunoglobulin G, Immunoglobulin M.
- chemical , biosynthesis : Antibodies, Helminth.
- chemical , immunology : Antigens, Helminth.
- immunology : Brugia, Dirofilaria immitis, Elephantiasis, Filarial, Filariasis, Filarioidea, Wuchereria, Wuchereria bancrofti.
- Animals, Counterimmunoelectrophoresis, Enzyme-Linked Immunosorbent Assay, Humans.
Abstract
Using the antigens prepared from adult worms of B. malayi and D. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. It was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. Of the two antigens used, B. malayi adult antigen was found to be superior to D. immitis antigen in the detection of filarial antibodies.
PubMed: 3311932
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H. Kumar<affiliation><nlm:affiliation>Immunology Laboratory, National Institute of Communicable Diseases, Delhi.</nlm:affiliation>
<wicri:noCountry code="subField">Delhi</wicri:noCountry>
</affiliation>
Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antibodies, Helminth (analysis)</term>
<term>Antibodies, Helminth (biosynthesis)</term>
<term>Antigens, Helminth (immunology)</term>
<term>Brugia (immunology)</term>
<term>Counterimmunoelectrophoresis</term>
<term>Dirofilaria immitis (immunology)</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Filariasis (immunology)</term>
<term>Filarioidea (immunology)</term>
<term>Humans</term>
<term>Immunoglobulin G (analysis)</term>
<term>Immunoglobulin M (analysis)</term>
<term>Wuchereria (immunology)</term>
<term>Wuchereria bancrofti (immunology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Anticorps antihelminthe (analyse)</term>
<term>Anticorps antihelminthe (biosynthèse)</term>
<term>Antigènes d'helminthe (immunologie)</term>
<term>Brugia (immunologie)</term>
<term>Contre-immunoélectrophorèse</term>
<term>Dirofilaria immitis (immunologie)</term>
<term>Filarioidea (immunologie)</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Filarioses (immunologie)</term>
<term>Humains</term>
<term>Immunoglobuline G (analyse)</term>
<term>Immunoglobuline M (analyse)</term>
<term>Test ELISA</term>
<term>Wuchereria (immunologie)</term>
<term>Wuchereria bancrofti (immunologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antibodies, Helminth</term>
<term>Immunoglobulin G</term>
<term>Immunoglobulin M</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Antibodies, Helminth</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Helminth</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Anticorps antihelminthe</term>
<term>Immunoglobuline G</term>
<term>Immunoglobuline M</term>
</keywords>
<keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Anticorps antihelminthe</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes d'helminthe</term>
<term>Brugia</term>
<term>Dirofilaria immitis</term>
<term>Filarioidea</term>
<term>Filariose lymphatique</term>
<term>Filarioses</term>
<term>Wuchereria</term>
<term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Brugia</term>
<term>Dirofilaria immitis</term>
<term>Elephantiasis, Filarial</term>
<term>Filariasis</term>
<term>Filarioidea</term>
<term>Wuchereria</term>
<term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Counterimmunoelectrophoresis</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Contre-immunoélectrophorèse</term>
<term>Humains</term>
<term>Test ELISA</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en">Using the antigens prepared from adult worms of B. malayi and D. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. It was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. Of the two antigens used, B. malayi adult antigen was found to be superior to D. immitis antigen in the detection of filarial antibodies.</div>
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<Abstract><AbstractText>Using the antigens prepared from adult worms of B. malayi and D. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. It was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. Of the two antigens used, B. malayi adult antigen was found to be superior to D. immitis antigen in the detection of filarial antibodies.</AbstractText>
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